Invention Grant
- Patent Title: Metabolically enhanced cyanobacterial cell for the production of ethanol
- Patent Title (中): 用于生产乙醇的代谢增强的蓝细菌细胞
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Application No.: US14305781Application Date: 2014-06-16
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Publication No.: US09127297B2Publication Date: 2015-09-08
- Inventor: Ulf Dühring , Heike Enke , Karl Ziegler , Torsten Schwecke
- Applicant: Algenol Biofuels Inc.
- Applicant Address: US FL Fort Myers
- Assignee: Algenol Biotech LLC
- Current Assignee: Algenol Biotech LLC
- Current Assignee Address: US FL Fort Myers
- Agent Lawrence B. Ebert; Suzanne G. Jepson
- Main IPC: C12N1/12
- IPC: C12N1/12 ; C12P7/06 ; C12N15/00 ; C12P19/34 ; C07H21/04 ; C07K1/00
Abstract:
A metabolically enhanced cyanobacterial cell for the production of ethanol is provided. The metabolically enhanced cyanobacterial cell for the production of ethanol comprises at least one recombinant gene encoding a pyruvate decarboxylase enzyme (Pdc) converting pyruvate to acetaldehyde, and at least one recombinant gene encoding a first Zn2+ dependent alcohol dehydrogenase enzyme (Adh) converting acetaldehyde to ethanol. The invention also provides a method for producing the metabolically enhanced cyanobacterium, a method for producing ethanol with the metabolically enhanced cyanobacterium, and a method for screening of alcohol dehydrogenase enzyme expressing cyanobacterial strains for the presence of NADPH-dependent native alcohol dehydrogenase enzymes.
Public/Granted literature
- US20140370574A1 Metabolically Enhanced Cyanobacterial Cell for the Production of Ethanol Public/Granted day:2014-12-18
Information query
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