Invention Grant
US09127302B2 System for the detection and enumeration of suspect target cells in a mixed cell population
有权
用于在混合细胞群体中检测和计数可疑靶细胞的系统
- Patent Title: System for the detection and enumeration of suspect target cells in a mixed cell population
- Patent Title (中): 用于在混合细胞群体中检测和计数可疑靶细胞的系统
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Application No.: US12067532Application Date: 2006-09-20
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Publication No.: US09127302B2Publication Date: 2015-09-08
- Inventor: John A Verrant , Arjan G. J. Tibbe , Brad Foulk , Joost F. Swennenhuis , Leon W. M. M. Terstappen , Mark Carle Connelly , Michael T. Kagan
- Applicant: John A Verrant , Arjan G. J. Tibbe , Brad Foulk , Joost F. Swennenhuis , Leon W. M. M. Terstappen , Mark Carle Connelly , Michael T. Kagan
- Applicant Address: US NJ Raritan
- Assignee: Janssen Diagnostics, LLC
- Current Assignee: Janssen Diagnostics, LLC
- Current Assignee Address: US NJ Raritan
- International Application: PCT/US2006/036656 WO 20060920
- International Announcement: WO2007/053245 WO 20070510
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/53 ; C12M1/00 ; C12M1/34 ; A61K39/395 ; C12Q1/34
Abstract:
The invention relates generally to the field of identification of DNA sequences, genes or chromosomes. Methods and composition to obtain Unique Sequence DNA probes are provided. Composition comprises of any double stranded DNA containing Unique Sequences from which the repetitive sequences are eliminated according to the method described in this invention. The invention also relates to the preservation of cells that have been identified after immunomagnetic selection and fluorescent labeling in order to further interrogate the cells of interest. Furthermore the invention relates to genetic analysis of cells that have been identified after immunomagnetic selection and fluorescent labeling.
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