Invention Grant
- Patent Title: Labelled nucleotides
- Patent Title (中): 标记核苷酸
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Application No.: US14073593Application Date: 2013-11-06
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Publication No.: US09127314B2Publication Date: 2015-09-08
- Inventor: Xiaohai Liu , John Milton , Silke Ruediger
- Applicant: ILLUMINA CAMBRIDGE LIMITED
- Applicant Address: GB Nr. Saffron Walden
- Assignee: Illumina Cambridge Limited
- Current Assignee: Illumina Cambridge Limited
- Current Assignee Address: GB Nr. Saffron Walden
- Agency: Jones Day
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H19/06 ; C07H19/10 ; C07H19/16 ; C07H19/20 ; C07H21/00

Abstract:
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterized in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) (wherein X is selected from the group comprising O, S, NH, and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH, and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
Public/Granted literature
- US20140141414A1 LABELLED NUCLEOTIDES Public/Granted day:2014-05-22
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