A downhole latch assembly has a plurality of latch keys including a primary latch key. A window joint is interconnected in a casing string positioned in a wellbore. A latch coupling having a latch profile is interconnected in the casing string downhole of the window joint. An orienting subassembly interconnected in the casing string has an orienting profile positioned uphole of the latch profile such that after operable engagement of the primary latch key with the orienting profile, axial alignment of the latch assembly with the latch coupling causes operable engagement of the latch keys with the latch profile.