In a system for optimizing natural gas production in response to real-time variations in wellbore parameters, a PLC or other wellsite intelligence technology is used to monitor liquid and gas production from the wellbore under friction-loaded conditions. Using baseline production data obtained during production tests, the PLC determines and initiates the appropriate operating mode for the wellbore to optimize a selected production criterion to suit measured wellbore parameters. The operating mode either a continuous clean-out mode, in which gas is continuously injected into the wellbore to control liquid loading, or an intermittent clean-out, in which liquid loading is regulated by intermittent gas injection. In preferred embodiments, the system uses bladder-type control valves having upstream and downstream solenoids, to control production tubing flow rate within a range between upper and lower set points.