Invention Grant
US09128014B2 High throughput and volumetric error resilient dilution with digital microfluidic based lab-on-a-chip
有权
基于数字微流体实验室芯片的高通量和体积误差弹性稀释
- Patent Title: High throughput and volumetric error resilient dilution with digital microfluidic based lab-on-a-chip
- Patent Title (中): 基于数字微流体实验室芯片的高通量和体积误差弹性稀释
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Application No.: US13809328Application Date: 2010-11-12
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Publication No.: US09128014B2Publication Date: 2015-09-08
- Inventor: Bhargab B. Bhattacharya , Sarmishtha Ghoshal , Sudip Roy , Krishnendu Chakrabarty
- Applicant: Bhargab B. Bhattacharya , Sarmishtha Ghoshal , Sudip Roy , Krishnendu Chakrabarty
- Applicant Address: IN Kolkata
- Assignee: INDIAN STATISTICAL INSTITUTE
- Current Assignee: INDIAN STATISTICAL INSTITUTE
- Current Assignee Address: IN Kolkata
- Agency: Workman Nydegger
- Priority: IN769/KOL/2010 20100715
- International Application: PCT/IB2010/002895 WO 20101112
- International Announcement: WO2012/007786 WO 20120119
- Main IPC: G01N1/38
- IPC: G01N1/38 ; B01F13/00 ; B01F15/04 ; B01L3/00 ; B01F3/08

Abstract:
Systems and methods are provided for producing fluids with desired concentration factors from the given supply of any two concentration factors, one greater than the target CF and one less than the target CF, of the same fluid. According to one embodiment, a method is provided that stores intermediate waste droplets from a sequence of mix and split steps and repeats certain steps of the sequence using the stored intermediate waste droplets. Such a method may produce additional target CF droplets faster than repeating the entire sequence. In another embodiment, a method of volumetric error resilient target CF droplet generation has been described, and includes reusing the stored intermediate waste droplets and involves a collection of capacitive sensing circuits associated with some electrode platforms.
Public/Granted literature
- US20130105318A1 HIGH THROUGHPUT AND VOLUMETRIC ERROR RESILIENT DILUTION WITH DIGITAL MICROFLUIDIC BASED LAB-ON-A-CHIP Public/Granted day:2013-05-02
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