A communication method used in a handheld communication device is provided. The communication method comprises the steps outlined below. Whether a voice communication is established is determined. When the voice communication is established, a sensing element is activated to determine whether the handheld communication device is operated in a hand mode. When the handheld communication device is not operated in the hand mode, an antenna module of the handheld communication device would be operated in a first operation frequency band to perform the voice communication. When the handheld communication device is operated in the hand mode, the antenna module of the handheld communication device would be operated in a second operation frequency band to perform the voice communication, in which the second operation frequency band is higher than the first operation frequency band. A handheld communication device is disclosed herein as well.