Invention Grant
US09133259B2 Cartilage oligomeric matrix protein (COMP)—growth factor complexes and uses thereof
有权
软骨低聚基质蛋白（COMP） - 生长因子复合物及其用途
- Patent Title: Cartilage oligomeric matrix protein (COMP)—growth factor complexes and uses thereof
- Patent Title (中): 软骨低聚基质蛋白（COMP） - 生长因子复合物及其用途
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Application No.: US13879399Application Date: 2011-09-14
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Publication No.: US09133259B2Publication Date: 2015-09-15
- Inventor: Dominik Haudenschild , Paul Di Cesare , Jasper Yik
- Applicant: Dominik Haudenschild , Paul Di Cesare , Jasper Yik
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2011/051610 WO 20110914
- International Announcement: WO2012/050714 WO 20120419
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/16 ; A61K38/17 ; A61K38/18 ; C07K14/00 ; C07K14/435 ; C07K14/475 ; C07K14/495 ; C07K14/51 ; C07K14/485 ; C07K14/78 ; A61L27/22 ; A61L27/38 ; A61L27/54 ; A61L27/58
Abstract:
The present invention relates to protein complexes or scaffold comprising cartilage oligomeric matrix protein (COMP) polypeptides bound to one or more growth factors, and methods of their use in promoting chondrogenesis and/or osteogenesis, and repair of cartilage and bone lesions.
Public/Granted literature
- US20130315889A1 CARTILAGE OLIGOMERIC MATRIX PROTEIN (COMP)-GROWTH FACTOR COMPLEXES AND USES THEREOF Public/Granted day:2013-11-28
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