Invention Grant
US09138427B2 Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
有权
S-亚硝基谷胱甘肽还原酶吡咯抑制剂作为治疗剂
- Patent Title: Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
- Patent Title (中): S-亚硝基谷胱甘肽还原酶吡咯抑制剂作为治疗剂
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Application No.: US14204849Application Date: 2014-03-11
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Publication No.: US09138427B2Publication Date: 2015-09-22
- Inventor: Jan Wasley , Gary J. Rosenthal , Xicheng Sun , Sarah Strong , Jian Qiu
- Applicant: N30 Pharmaceuticals, Inc.
- Applicant Address: US CO Boulder
- Assignee: Nivalis Therapeutics, Inc.
- Current Assignee: Nivalis Therapeutics, Inc.
- Current Assignee Address: US CO Boulder
- Agency: Swanson & Bratschun, L.L.C.
- Main IPC: C07D207/337
- IPC: C07D207/337 ; C07D401/14 ; C07D417/04 ; C07D413/10 ; C07D417/14 ; C07D409/04 ; A61K31/4178 ; C07D207/327 ; C07D401/04 ; C07D401/10 ; C07D401/12 ; C07D403/04 ; C07D403/10 ; C07D403/12 ; C07D403/14 ; C07D405/04 ; C07D405/10 ; C07D405/12 ; C07D409/10 ; C07D409/12 ; C07D409/14 ; C07D413/04 ; C07D413/12 ; C07D413/14 ; C07D417/10 ; A61K31/402 ; A61K31/4025

Abstract:
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and methods of making and using the same.
Public/Granted literature
- US20140194425A1 Novel Pyrrole Inhibitors of S-Nitrosoglutathione Reductase as Therapeutic Agents Public/Granted day:2014-07-10
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