An apparatus for loading a wheelchair into a vehicle and automatically storing the wheelchair within an enclosure that protects the wheelchair and the mechanisms of the apparatus from exposure to weather during transportation is disclosed. The Wheelchair Transportation Loading and Storage Apparatus would primarily be used to automatically load into and store a wheelchair within an enclosure, which protects the wheelchair and the apparatus' mechanisms from exposure to weather during transportation, which is mounted in a portion of a pick-up truck bed as to allow for substantial use of the pickup bed for other purposes such as the transportation and storage of tools and materials, and which appears as an ordinary pick-up-truck-bed tool box when it is in the stowed position. The Wheelchair Transportation Loading and Storage Apparatus comprises a wheelchair hoist, a weather-resistant enclosure and a control module which may be operated remotely.