A non-resorbable wound dressing can include a plug made from polytetrafluoroethylene (PTFE). The plug can have a three-dimensional shape. The plug can be substantially cylindrical. The PTFE can have a high density and be expanded. The PTFE can be non-porous or have a porosity of less than about 0.4 microns. The PTFE can also be unsintered and unexpanded. A method of regenerating alveolar bone includes placing a PTFE plug in a cavity formed in an alveolar bone. Placing the plug in the cavity can include contacting at least a portion of a peripheral surface of the plug with the gingival tissue surrounding the cavity. The method can also include inserting a bone graft material in the cavity before placing the plug in the cavity.