Invention Grant
- Patent Title: Itraconazole compositions with improved bioavailability
- Patent Title (中): 具有改善的生物利用度的伊曲康唑组合物
-
Application No.: US13923459Application Date: 2013-06-21
-
Publication No.: US09149431B2Publication Date: 2015-10-06
- Inventor: Gunther Berndl , Matthias Degenhardt , Markus Mägerlein , Gerrit Dispersyn
- Applicant: ABBOTT GMBH & CO. KG , BARRIER THERAPEUTICS
- Applicant Address: DE Wiesbaden US NJ Princeton
- Assignee: Abbvie Deutschland GmbH & Co KG,Barrier Therapeutics, Inc.
- Current Assignee: Abbvie Deutschland GmbH & Co KG,Barrier Therapeutics, Inc.
- Current Assignee Address: DE Wiesbaden US NJ Princeton
- Agency: Saul Ewing LLP
- Agent Peter C. Lauro, Esq.
- Main IPC: A61K9/10
- IPC: A61K9/10 ; A61K31/496 ; A61K9/14
Abstract:
A solid dispersion product comprising itraconazole and hydroxypropyl methylcellulose, which satisfies the Formula 0.35>ΔHtr (1) (wherein ΔHtr represents the endotherm (J/g) accompanying a transition at about 240° C.). The solid dispersion product shows an improved bioavailability.
Public/Granted literature
- US20140005204A1 ITRACONAZOLE COMPOSITIONS WITH IMPROVED BIOAVAILABILITY Public/Granted day:2014-01-02
Information query
