Invention Grant
- Patent Title: Crystalline naloxol-PEG conjugate
- Patent Title (中): 结晶纳洛酮-PEG缀合物
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Application No.: US14645347Application Date: 2015-03-11
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Publication No.: US09149539B1Publication Date: 2015-10-06
- Inventor: Bengt Aslund , Carl-Johan Aurell , Martin Hans Bohlin , Tesfai Sebhatu , Bo Ingvar Ymen , Eric Thomas Healy , David Richard Jensen , David Thomas Jonaitis , Stephan Parent
- Applicant: AstraZeneca AB , Nektar Therapeutics
- Applicant Address: SE Sodertalje US CA San Francisco
- Assignee: ASTRAZENECA AB,NEKTAR THERAPEUTICS
- Current Assignee: ASTRAZENECA AB,NEKTAR THERAPEUTICS
- Current Assignee Address: SE Sodertalje US CA San Francisco
- Agency: Jones Day
- Main IPC: C07D489/04
- IPC: C07D489/04 ; A61K47/48 ; C07C55/07
Abstract:
Naloxol-polyethylene glycol conjugates of the formula: are provided in oxalate or phosphate salt forms including crystalline forms. Methods of preparing the salt forms and pharmaceutical compositions comprising the salt forms are also provided.
Public/Granted literature
- US20150283257A1 CRYSTALLINE NALOXOL-PEG CONJUGATE Public/Granted day:2015-10-08
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