Invention Grant
US09149659B2 Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles 有权
用于增加皮肤中透明质酸合成的化妆品组合物及其用于修复皱纹的用途

Cosmetic composition for increasing hyaluronic acid synthesis in skin and its use for repairing wrinkles
Abstract:
The present invention relates to a skin composition which has an excellent effect on smoothing or repairing wrinkles. The composition comprises Palmitoyl Tripeptide-38 (Palmitoyl-Lysyl-Dioxymethionyl-Lysine) and Piper nigrum (Pepper) seed Extract which combination has been found to result in a synergistic effect on hyaluronan synthase 1 (HAS1) mRNA expression in human fibroblasts. The hyaluronan synthase is responsible for the synthesis of hyaluronan (hyaluronic acid) in skin. Hyaluronic acid is a constituent of the extracellular matrix of the skin and responsible for space filling, tissue repair and retention of moisture.
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