Invention Grant
US09150521B2 Methods of preventing and treating diabetes by inhibiting serotonin synthesis
有权
通过抑制5-羟色胺合成来预防和治疗糖尿病的方法
- Patent Title: Methods of preventing and treating diabetes by inhibiting serotonin synthesis
- Patent Title (中): 通过抑制5-羟色胺合成来预防和治疗糖尿病的方法
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Application No.: US14375722Application Date: 2013-01-31
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Publication No.: US09150521B2Publication Date: 2015-10-06
- Inventor: Gerard Karsenty , Grzegorz Sumara , Olga Sumara
- Applicant: Gerard Karsenty , Grzegorz Sumara , Olga Sumara
- Applicant Address: US NY New York
- Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee: The Trustees of Columbia University in the City of New York
- Current Assignee Address: US NY New York
- Agency: Kenyon & Kenyon LLP
- International Application: PCT/US2013/024177 WO 20130131
- International Announcement: WO2013/116538 WO 20130808
- Main IPC: C07D239/47
- IPC: C07D239/47 ; A61K45/06 ; A61K31/513 ; A61K31/505 ; C12Q1/26 ; G01N33/94
Abstract:
The present invention provides methods and therapeutic agents for lowering serum or plasma serotonin levels in a patient in order to prevent or treat diabetes. In preferred embodiments, the patient is known to have, or to be at risk for, diabetes and the agents are TPH1 inhibitors.
Public/Granted literature
- US20140378489A1 METHODS OF PREVENTING AND TREATING DIABETES BY INHIBITING SEROTONIN SYNTHESIS Public/Granted day:2014-12-25
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