Invention Grant
US09150525B2 Heteroaryl compounds useful as inhibitors of E1 activating enzymes
有权
可用作E1活化酶抑制剂的杂芳基化合物
- Patent Title: Heteroaryl compounds useful as inhibitors of E1 activating enzymes
- Patent Title (中): 可用作E1活化酶抑制剂的杂芳基化合物
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Application No.: US14480513Application Date: 2014-09-08
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Publication No.: US09150525B2Publication Date: 2015-10-06
- Inventor: Christopher F. Claiborne , Stephen Critchley , Steven P. Langston , Hirotake Mizutani , Edward J. Olhava , Stephane Peluso , Stepan Vyskocil , Gabriel S. Weatherhead
- Applicant: Millennium Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Main IPC: C07D251/48
- IPC: C07D251/48 ; A61K31/53 ; C07D251/18
Abstract:
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
Public/Granted literature
- US20150183753A1 HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF E1 ACTIVATING ENZYMES Public/Granted day:2015-07-02
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