Invention Grant
US09150530B2 Esters of 4, 9-dihydroxy-naphtho [2, 3-b] furans for disease therapies
有权
用于疾病治疗的4,9-二羟基 - 萘并[2,3-b]呋喃的酯
![Esters of 4, 9-dihydroxy-naphtho [2, 3-b] furans for disease therapies](/docs/US/2015-10-06/US09150530B2/abs.jpg.600x600.jpg)
- Patent Title: Esters of 4, 9-dihydroxy-naphtho [2, 3-b] furans for disease therapies
- Patent Title (中): 用于疾病治疗的4,9-二羟基 - 萘并[2,3-b]呋喃的酯
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Application No.: US14002986Application Date: 2011-03-04
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Publication No.: US09150530B2Publication Date: 2015-10-06
- Inventor: Zhiwei Jiang , Aijin Wang , Hongwei Hu , Jiali Xu , Yuesong Hu , Xian Li , Yan Ye , Jie Wang , Qinglong Li
- Applicant: Zhiwei Jiang , Aijin Wang , Hongwei Hu , Jiali Xu , Yuesong Hu , Xian Li , Yan Ye , Jie Wang , Qinglong Li
- Applicant Address: CN Zhoushan, Zhejiang
- Assignee: Zhoushan Haizhongzhou Xinsheng Pharmaceuticals Co., Ltd.
- Current Assignee: Zhoushan Haizhongzhou Xinsheng Pharmaceuticals Co., Ltd.
- Current Assignee Address: CN Zhoushan, Zhejiang
- Agency: Choate, Hall & Stewart, LLP
- Agent Fangli Chen; John P. Rearick
- International Application: PCT/CN2011/000357 WO 20110304
- International Announcement: WO2012/119265 WO 20120913
- Main IPC: A61K31/34
- IPC: A61K31/34 ; C07D307/92 ; A61K31/343 ; A61K31/665 ; A61K45/06 ; C07F9/655
![Esters of 4, 9-dihydroxy-naphtho [2, 3-b] furans for disease therapies](/abs-image/US/2015/10/06/US09150530B2/abs.jpg.150x150.jpg)
Abstract:
The present invention discloses esters of 4,9-dihydroxy-naphtho[2,3-b]furans and methods of making and using the same. The present invention also discloses conversion of the esters into therapeutically active 4,9-dihydroxy-naphtho[2,3-b]furans in vivo. The present invention furthermore discloses pharmaceutical compositions comprising the esters of 4,9-dihydroxy-naphtho[2,3-b]furans for the treatment of various indications including proliferative diseases.
Public/Granted literature
- US20130345176A1 NOVEL ESTERS OF 4, 9-DIHYDROXY-NAPHTHO [2, 3-b] FURANS FOR DISEASE THERAPIES Public/Granted day:2013-12-26
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