Invention Grant
US09150566B2 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-YL)picolinamide derivatives as orexin receptor antagonists
有权
2-（1,2,3-三唑-2-基）苯甲酰胺和3-（1,2,3-三唑-2-基）吡啶甲酰胺衍生物作为食欲素受体拮抗剂
- Patent Title: 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-YL)picolinamide derivatives as orexin receptor antagonists
- Patent Title (中): 2-（1,2,3-三唑-2-基）苯甲酰胺和3-（1,2,3-三唑-2-基）吡啶甲酰胺衍生物作为食欲素受体拮抗剂
-
Application No.: US14357159Application Date: 2012-11-07
-
Publication No.: US09150566B2Publication Date: 2015-10-06
- Inventor: Martin Bolli , Christoph Boss , Christine Brotschi , Bibia Heidmann , Thierry Sifferlen , Jodi T. Williams
- Applicant: Martin Bolli , Christoph Boss , Christine Brotschi , Bibia Heidmann , Thierry Sifferlen , Jodi T. Williams
- Applicant Address: CH Allschwil
- Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates LLC
- Priority: WOPCT/IB2011/054976 20111108
- International Application: PCT/IB2012/056218 WO 20121107
- International Announcement: WO2013/068935 WO 20130516
- Main IPC: C07D413/10
- IPC: C07D413/10 ; C07D413/14 ; C07D417/14 ; A61K31/5377
Abstract:
The present invention relates to 2-(1,2,3-triazol-2-yl)benzamide and 3-(1,2,3-triazol-2-yl)picolinamide derivatives of formula (I) wherein Ar1, Q, and R1 to R5 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.
Public/Granted literature
Information query
