Invention Grant
- Patent Title: Compositions and methods for modulating FXR
- Patent Title (中): 用于调节FXR的组合物和方法
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Application No.: US13993138Application Date: 2011-11-30
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Publication No.: US09150568B2Publication Date: 2015-10-06
- Inventor: David C. Tully , Paul Vincent Rucker , Phillip B. Alper , Daniel Mutnick , Donatella Chianelli
- Applicant: David C. Tully , Paul Vincent Rucker , Phillip B. Alper , Daniel Mutnick , Donatella Chianelli
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Emily Tongco Wu
- International Application: PCT/US2011/062724 WO 20111130
- International Announcement: WO2012/087519 WO 20120628
- Main IPC: C07D451/06
- IPC: C07D451/06 ; C07D519/00 ; C07H17/00 ; A61K45/06 ; A61K31/46 ; A61K31/506 ; A61K31/497 ; A61K31/501 ; A61K31/4709 ; A61K31/5025 ; A61K31/706 ; C07D471/04 ; C07D487/04
Abstract:
The present invention relates to compounds of Formula (I), a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesiod X receptors (FXR).
Public/Granted literature
- US20130331349A1 COMPOSITIONS AND METHODS FOR MODULATING FXR Public/Granted day:2013-12-12
Information query
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