Invention Grant
US09150578B2 5,8-dihydro-6H-pyrazolo[3,4-h]quinazolines as IGF-1R/IR inhibitors
有权
5,8-二氢-6H-吡唑并[3,4-h]喹唑啉作为IGF-1R / IR抑制剂
- Patent Title: 5,8-dihydro-6H-pyrazolo[3,4-h]quinazolines as IGF-1R/IR inhibitors
- Patent Title (中): 5,8-二氢-6H-吡唑并[3,4-h]喹唑啉作为IGF-1R / IR抑制剂
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Application No.: US13746411Application Date: 2013-01-22
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Publication No.: US09150578B2Publication Date: 2015-10-06
- Inventor: Matthias Treu
- Applicant: Matthias Treu
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: EP12152193 20120123
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D487/04 ; C07D487/14
![5,8-dihydro-6H-pyrazolo[3,4-h]quinazolines as IGF-1R/IR inhibitors](/abs-image/US/2015/10/06/US09150578B2/abs.jpg.150x150.jpg)
Abstract:
The present invention encompasses compounds of general formula (I) wherein the groups R1 to R6, A, B, C, n, p, q and r are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, pharmaceutical preparations which contain compounds of this kind and their use as medicaments.
Public/Granted literature
- US20130190305A1 NEW 5,8-DIHYDRO-6H-PYRAZOLO[3,4-H]QUINAZOLINES AS IGF-1R/IR INHIBITORS Public/Granted day:2013-07-25
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