Invention Grant
- Patent Title: Nicotinic receptor compounds
- Patent Title (中): 烟碱受体化合物
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Application No.: US14368111Application Date: 2012-12-26
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Publication No.: US09150581B2Publication Date: 2015-10-06
- Inventor: Frank Ivy Carroll , Pauline Wanjiku Ondachi , Hernan A. Navarro , M. Imad Damaj , James H. Woods , Emily M. Jutkiewicz
- Applicant: RESEARCH TRIANGLE INSTITUTE , THE REGENTS OF THE UNIVERSITY OF MICHIGAN , VIRGINIA COMMONWEALTH UNIVERSITY
- Applicant Address: US NC Research Triangle Park US MI Ann Arbor US VA Richmond
- Assignee: RESEARCH TRIANGLE INSTITUTE,THE REGENTS OF THE UNIVERSITY OF MICHIGAN,VIRGINIA COMMONWEALTH UNIVERSITY
- Current Assignee: RESEARCH TRIANGLE INSTITUTE,THE REGENTS OF THE UNIVERSITY OF MICHIGAN,VIRGINIA COMMONWEALTH UNIVERSITY
- Current Assignee Address: US NC Research Triangle Park US MI Ann Arbor US VA Richmond
- Agency: Hultquist, PLLC
- Agent Mary B. Grant
- International Application: PCT/US2012/071611 WO 20121226
- International Announcement: WO2013/101802 WO 20130704
- Main IPC: C07D487/08
- IPC: C07D487/08
Abstract:
Compounds and compositions for promoting smoking cessation or decreasing tobacco use or nicotine addiction are provided. The compounds are 2′-fluoro-3′-(substituted phenyl) deschloroepibatidine analogs. The compounds have been found to modulate neuronal nicotine acetylcholine receptors and are useful in methods for the treatment of conditions or disorders influenced by the modulation of neuronal nicotinic acetylcholine receptors.
Public/Granted literature
- US20150307502A9 NICOTINIC RECEPTOR COMPOUNDS Public/Granted day:2015-10-29
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