Invention Grant
US09150583B2 Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation
有权
呋喃并[3,4-c]喹啉衍生物,含有这些化合物的药物,其用途和制备方法
- Patent Title: Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation
- Patent Title (中): 呋喃并[3,4-c]喹啉衍生物,含有这些化合物的药物,其用途和制备方法
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Application No.: US13586977Application Date: 2012-08-16
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Publication No.: US09150583B2Publication Date: 2015-10-06
- Inventor: Thomas Trieselmann , Dieter Hamprecht , Holger Wagner
- Applicant: Thomas Trieselmann , Dieter Hamprecht , Holger Wagner
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; David L. Kershner; Usha R. Patel
- Priority: EP11177808 20110817
- Main IPC: C07D491/20
- IPC: C07D491/20 ; A61K31/4747 ; A61K45/06
![Furo[3,4-c]quinoline derivatives, medicaments containing such compounds, their use and process for their preparation](/abs-image/US/2015/10/06/US09150583B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds defined by formula I wherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this protein.
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