Invention Grant
US09150586B2 Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
有权
哌啶子基 - 二氢噻吩并嘧啶亚砜及其用于治疗COPD和哮喘的用途
- Patent Title: Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma
- Patent Title (中): 哌啶子基 - 二氢噻吩并嘧啶亚砜及其用于治疗COPD和哮喘的用途
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Application No.: US14239818Application Date: 2012-03-15
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Publication No.: US09150586B2Publication Date: 2015-10-06
- Inventor: Pascale A. J. Pouzet , Peter Nickolaus , Ulrike Werthmann , Rogelio P. Frutos , Bing-Shiou Yang , Soojin Kim , Jason Alan Mulder , Nitinchandra Patel , Chris H. Senanayake , Thomas G. Tampone , Xudong Wei
- Applicant: Pascale A. J. Pouzet , Peter Nickolaus , Ulrike Werthmann , Rogelio P. Frutos , Bing-Shiou Yang , Soojin Kim , Jason Alan Mulder , Nitinchandra Patel , Chris H. Senanayake , Thomas G. Tampone , Xudong Wei
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Timothy X. Witkowski
- International Application: PCT/EP2012/066104 WO 20120315
- International Announcement: WO2013/026797 WO 20130228
- Main IPC: C07D239/02
- IPC: C07D239/02 ; C07D495/04 ; C07D401/04 ; C07C213/00 ; A61K31/519 ; A61K45/06

Abstract:
The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms and wherein R is Cl and wherein R may be located either in the para-, meta- or ortho-position of Ring A, wherein S* is a sulphur atom that represents a chiral center, and all pharmaceutically acceptable salts, enantiomers and racemates, hydrates and solvates thereof and the use of these compounds for the treatment of inflammatory or allergic diseases of the respiratory tract such as COPD or asthma.
Public/Granted literature
- US20150148322A1 NOVEL PIPERIDINO-DIHYDROTHIENOPYRIMIDINE SULFOXIDES AND THEIR USE FOR TREATING COPD AND ASTHMA Public/Granted day:2015-05-28
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