Invention Grant
- Patent Title: Anti-C-met antibody and methods of use thereof
- Patent Title (中): 抗C-met抗体及其使用方法
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Application No.: US13818283Application Date: 2011-08-30
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Publication No.: US09150655B2Publication Date: 2015-10-06
- Inventor: Han-Chung Wu , Ruei-Min Lu
- Applicant: Han-Chung Wu , Ruei-Min Lu
- Applicant Address: TW Nankang, Taipei US MD Bethesda
- Assignee: ACADEMIA SINICA,Chi-Ming Liang
- Current Assignee: ACADEMIA SINICA,Chi-Ming Liang
- Current Assignee Address: TW Nankang, Taipei US MD Bethesda
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- International Application: PCT/US2011/049763 WO 20110830
- International Announcement: WO2012/030842 WO 20120308
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K9/127 ; A61K47/48 ; A61K49/00 ; A61K9/00 ; A61K47/24 ; A61K39/00

Abstract:
Antibodies that bind to c-Met are provided herein, as well as related compositions and methods of use. Methods of use encompass cancer therapies and diagnostics. In certain embodiments, antibodies bind mammalian cell surface antigen (e.g., cancer cell surface antigen). The antibodies can also be endocytosed upon binding to cells. Cells that can be targeted by the antibodies include carcinomas, such as those in lung, kidney, liver, stomach, breast, and brain, etc.
Public/Granted literature
- US20130209365A1 Anti-C-Met Antibody and Methods of Use Thereof Public/Granted day:2013-08-15
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