Invention Grant
- Patent Title: Human antibodies against tissue factor and methods of use thereof
- Patent Title (中): 针对组织因子的人抗体及其使用方法
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Application No.: US13133811Application Date: 2009-12-09
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Publication No.: US09150658B2Publication Date: 2015-10-06
- Inventor: Sandra Verploegen , David P. E. Satijn , Rene Hoet , Paul Parren , Jan Van De Winkel , Vibeke Miller Breinholt , Eva Ehrnrooth , Ole Baadsgaard , Tom Vink , Willem Karel Bleeker , Mischa Houtkamp , Maroeska Oudshoorn , Rob N. De Jong
- Applicant: Sandra Verploegen , David P. E. Satijn , Rene Hoet , Paul Parren , Jan Van De Winkel , Vibeke Miller Breinholt , Eva Ehrnrooth , Ole Baadsgaard , Tom Vink , Willem Karel Bleeker , Mischa Houtkamp , Maroeska Oudshoorn , Rob N. De Jong
- Applicant Address: DK Copenhagen
- Assignee: GENMAB A/S
- Current Assignee: GENMAB A/S
- Current Assignee Address: DK Copenhagen
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Christopher L. Frank
- Priority: DK200801744 20081209
- International Application: PCT/EP2009/066755 WO 20091209
- International Announcement: WO2010/066803 WO 20100617
- Main IPC: C07K16/36
- IPC: C07K16/36 ; A61K39/395

Abstract:
Isolated human monoclonal antibodies which bind to human TF and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
Public/Granted literature
- US20110300156A1 HUMAN ANTIBODIES AGAINST TISSUE FACTOR Public/Granted day:2011-12-08
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