Invention Grant
- Patent Title: Differentiation of human embryonic stem cells
- Patent Title (中): 人类胚胎干细胞的分化
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Application No.: US12970330Application Date: 2010-12-16
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Publication No.: US09150833B2Publication Date: 2015-10-06
- Inventor: Jean Xu
- Applicant: Jean Xu
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Lois A. Gianneschi
- Main IPC: C12N5/07
- IPC: C12N5/07 ; C12N5/00 ; C12N5/071
Abstract:
The present invention provides methods to promote the differentiation of pluripotent stem cells into insulin producing cells. In particular, the present invention provides a method to produce cells expressing markers characteristic of the pancreatic endocrine lineage that co-express NKX6.1 and insulin and minimal amounts of glucagon.
Public/Granted literature
- US20110151560A1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Public/Granted day:2011-06-23
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