Invention Grant
US09150836B2 Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
有权
适用于改变油籽植物中多不饱和脂肪酸水平和油质酵母的Delta-15去饱和酶
- Patent Title: Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
- Patent Title (中): 适用于改变油籽植物中多不饱和脂肪酸水平和油质酵母的Delta-15去饱和酶
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Application No.: US13897556Application Date: 2013-05-20
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Publication No.: US09150836B2Publication Date: 2015-10-06
- Inventor: Howard Glenn Damude , Narendra S Yadav
- Applicant: E.I. du Pont de Nemours and Company
- Applicant Address: US DE Wilmington
- Assignee: E I DU PONT DE NEMOURS AND COMPANY
- Current Assignee: E I DU PONT DE NEMOURS AND COMPANY
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N15/82
- IPC: C12N15/82 ; C12N9/02 ; C12P7/64

Abstract:
The present invention relates to fungal Δ-15 fatty acid desaturases that are able to catalyze the conversion of linoleic acid (18:2, LA) to alpha-linolenic acid (18:3, ALA). Nucleic acid sequences encoding the desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising the desaturase genes, and recombinant host plants and microorganisms expressing increased levels of the desaturases are described. Methods of increasing production of specific omega-3 and omega-6 fatty acids by over-expression of the Δ-15 fatty acid desaturases are also described herein.
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