Invention Grant
- Patent Title: Quantification of IR-A and IR-B for tumor classification
- Patent Title (中): 用于肿瘤分类的IR-A和IR-B的定量
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Application No.: US13501542Application Date: 2010-10-11
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Publication No.: US09150927B2Publication Date: 2015-10-06
- Inventor: Jiaqi Huang , Chris Morehouse , Yihong Yao , Theresa Lavalle
- Applicant: Jiaqi Huang , Chris Morehouse , Yihong Yao , Theresa Lavalle
- Applicant Address: US MD Gaithersburg
- Assignee: MedImmune, LLC
- Current Assignee: MedImmune, LLC
- Current Assignee Address: US MD Gaithersburg
- International Application: PCT/US2010/052173 WO 20101011
- International Announcement: WO2011/046871 WO 20110421
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Without limitation, this disclosure relates to compositions and methods for detecting and quantifying the expression of insulin receptor isoform A (IR-A) and/or insulin receptor isoform B (IR-B) in a tissue sample. The disclosure also relates to methods of diagnosis and classification based at least in part upon detecting and quantifying the expression of insulin receptor isoform A (IR-A) and/or insulin B (IR-B) in a tissue sample. Methods of treating a subject based upon such a classification are among additional aspects of the disclosure presented herein.
Public/Granted literature
- US20120283121A1 Quantification of IR-A and IR-B for Tumor Classification Public/Granted day:2012-11-08
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