A prosthetic femoral component (10) for an orthopaedic prosthesis has a canted patellar groove adapted for optimal patella/component interaction, with the component configured to have a medial or lateral cant depending upon the method of implantation. The femoral component defines a distal “component transverse plane,” which is a plane tangent to the distal-most points of the component condyles (12,14). In a “mechanical” implantation, the component transverse plane is substantially normal to the mechanical femoral axis of the femur after the component has been implanted. Where the femoral component is configured to be “mechanically oriented” in this manner, the component has a medially canted patellar groove. On the other hand, an “anatomic” implantation is one in which, after the component has been implanted, the component transverse plane is substantially parallel to an “anatomic” transverse plane. The anatomic transverse plane is perpendicular to the anatomic axis of the femur from a sagittal view, and is inclusive of a line connecting the distal-most points of the natural femoral condyles before resection. Where the femoral component is configured to be “anatomically oriented” in this way, the component has a non-canted or slightly laterally canted patellar groove.