Invention Grant
- Patent Title: Patch
- Patent Title (中): 补丁
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Application No.: US13882565Application Date: 2011-11-02
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Publication No.: US09173855B2Publication Date: 2015-11-03
- Inventor: Hiroko Udagawa , Yoshikazu Inaba , Yukihiko Noda , Kumi Obata , Hiroto Terashima
- Applicant: Hiroko Udagawa , Yoshikazu Inaba , Yukihiko Noda , Kumi Obata , Hiroto Terashima
- Applicant Address: JP Tokyo
- Assignee: SEKISUI MEDICAL CO., LTD.
- Current Assignee: SEKISUI MEDICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2010-246906 20101102
- International Application: PCT/JP2011/075354 WO 20111102
- International Announcement: WO2012/060431 WO 20120510
- Main IPC: A61F13/00
- IPC: A61F13/00 ; A61K31/415 ; A61F13/02 ; A61K9/70 ; A61K31/4168

Abstract:
Disclosed is a patch which is a formulation including deposited clonidine crystals and provides stable transdermal absorbability even after storage at varying temperatures. The patch disclosed includes a backing and a medicated layer integrally superposed on one surface of the backing. The medicated layer contains: 5 to 30% by weight of clonidine including clonidine in a crystallized state; 25 to 90% by weight of a macromolecular base (A) having a viscosity-average molecular weight of 800,000 or larger; and 5 to 60% by weight of a liquid additive capable of dissolving the clonidine. The weight ratio of the liquid additive to the macromolecular base (A) [the liquid additive/the macromolecular base (A)] is 0.1 to 2.0.
Public/Granted literature
- US20130261572A1 PATCH Public/Granted day:2013-10-03
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