Invention Grant
US09173880B2 Stabilized formulations containing anti-interleukin-6 receptor (IL-6R) antibodies
有权
含有抗白细胞介素-6受体（IL-6R）抗体的稳定制剂
- Patent Title: Stabilized formulations containing anti-interleukin-6 receptor (IL-6R) antibodies
- Patent Title (中): 含有抗白细胞介素-6受体（IL-6R）抗体的稳定制剂
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Application No.: US12986223Application Date: 2011-01-07
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Publication No.: US09173880B2Publication Date: 2015-11-03
- Inventor: Daniel B. Dix , Kenneth S. Graham , Douglas Kamen , Scott M. Walsh
- Applicant: Daniel B. Dix , Kenneth S. Graham , Douglas Kamen , Scott M. Walsh
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Alston & Bird LLP
- Agent Joseph Zahner
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/485 ; A61K9/00 ; C07K16/24 ; A61K47/18 ; A61K47/26
Abstract:
The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-6 receptor (hIL-6R). The formulations may contain, in addition to an anti-hIL-6R antibody, at least one amino acid, at least one sugar, and/or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
Public/Granted literature
- US20110171241A1 Stabilized Formulations Containing Anti-Interleukin-6 (IL-6) Antibodies Public/Granted day:2011-07-14
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