Invention Grant
US09174966B2 Crystalline forms of 6-(1H-imidazol-1-yl)-2-phenylquinazoline 有权
6-(1H-咪唑-1-基)-2-苯基喹唑啉的结晶形式

Crystalline forms of 6-(1H-imidazol-1-yl)-2-phenylquinazoline
Abstract:
The present invention relates to the solid state of 6-(1H-imidazol-1-yl)-2-phenylquinazoline (I) and therefore to novel crystalline forms of the base and of pharmaceutically acceptable salts and solvates thereof, and also to methods for preparing them, to the respective pharmaceutical formulations and to their therapeutic use. Compound (I) may be obtained as the free base in five different crystalline forms, three polymorphic forms and two hydrates. Some pharmaceutically acceptable salts of (I) that have physicochemical characteristics acceptable for pharmaceutical development were obtained, and the respective polymorphic forms and/or hydrates were characterized.
Public/Granted literature
Information query
Patent Agency Ranking
0/0