Invention Grant
- Patent Title: Compounds for the treatment of proliferative disorders
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Application No.: US13956534Application Date: 2013-08-01
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Publication No.: US09175022B2Publication Date: 2015-11-03
- Inventor: Zachary Demko , Christopher Borella , Shoujun Chen , Lijun Sun
- Applicant: Synta Pharmaceuticals Corp.
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Main IPC: A61K31/4192
- IPC: A61K31/4192 ; A61K31/422 ; A61K31/4439 ; A61K31/4709 ; A61K31/4725 ; A61K31/501 ; A61K31/506 ; A61K31/675 ; C07F9/6518 ; C07D249/06 ; C07D401/04 ; C07D401/14 ; C07D403/04 ; C07D403/14 ; C07D405/14 ; C07D401/10 ; C07D403/10 ; C07D403/12 ; C07D405/04 ; C07D413/10
Abstract:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
Public/Granted literature
- US20130338112A1 COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Public/Granted day:2013-12-19
Information query
