Invention Grant
- Patent Title: Oligopeptide sequence specifically bonding to phenylboronic acid group
- Patent Title (中): 特异性结合苯基硼酸基团的寡肽序列
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Application No.: US13982755Application Date: 2012-01-30
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Publication No.: US09175035B2Publication Date: 2015-11-03
- Inventor: Tomohiro Konno , Kazuhiko Ishihara , Hirokazu Nishida
- Applicant: Tomohiro Konno , Kazuhiko Ishihara , Hirokazu Nishida
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: HITACHI, LTD.,THE UNIVERSITY OF TOKYO
- Current Assignee: HITACHI, LTD.,THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Baker Botts, L.L.P.
- Priority: JP2011-018163 20110131
- International Application: PCT/JP2012/051933 WO 20120130
- International Announcement: WO2012/105471 WO 20120809
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K39/21 ; C07K1/22 ; C07K17/06 ; C07K17/08 ; C07K17/14 ; C12N9/02 ; G01N33/543

Abstract:
An object of the present invention is to provide, as a method for immobilizing a protein molecule, protein immobilization method and means in which orientation of a molecule to be immobilized can be controlled, the molecule can be stably immobilized without a complicated process and a chemical group used for immobilization does not affect the activity and the function of the protein. Specifically, the present invention relates to a method for immobilizing a molecule including the steps of forming a labeled molecule by attaching a label peptide sequence comprising a hydroxyl group-containing amino acid to a molecule; and bringing a molecule having a phenylboronic acid group into contact with the labeled molecule, to capture the labeled molecule by the molecule having a phenylboronic acid group.
Public/Granted literature
- US20130344590A1 OLIGOPEPTIDE SEQUENCE SPECIFICALLY BONDING TO PHENYLBORONIC ACID GROUP Public/Granted day:2013-12-26
Information query
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