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US09175040B2 Immunotherapeutic peptides against neuronal and brain tumors and related methods and compositions 有权
针对神经元和脑肿瘤的免疫治疗肽及相关方法和组合物

Immunotherapeutic peptides against neuronal and brain tumors and related methods and compositions
Abstract:
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 11 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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