Invention Grant
US09175069B2 Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
有权
通过循环给药产生的针对流感病毒的单克隆抗体及其用途
- Patent Title: Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
- Patent Title (中): 通过循环给药产生的针对流感病毒的单克隆抗体及其用途
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Application No.: US14162354Application Date: 2014-01-23
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Publication No.: US09175069B2Publication Date: 2015-11-03
- Inventor: Adolfo Garcia-Sastre , Peter Palese , Taia T. Wang
- Applicant: Icahn School of Medicine at Mount Sinai
- Applicant Address: US NY New York
- Assignee: Icahn School of Medicine at Mount Sinai
- Current Assignee: Icahn School of Medicine at Mount Sinai
- Current Assignee Address: US NY New York
- Agency: Jones Day
- Main IPC: C07K16/10
- IPC: C07K16/10 ; G01N33/569 ; A61K39/00
Abstract:
Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes. Also provided herein are compositions comprising such antibodies and methods of using such antibodies to diagnose, prevent or treat Influenza virus disease.
Public/Granted literature
- US20140170163A1 MONOCLONAL ANTIBODIES AGAINST INFLUENZA VIRUS GENERATED BY CYCLICAL ADMINISTRATION AND USES THEREOF Public/Granted day:2014-06-19
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