Invention Grant
- Patent Title: Anti-GDF15 antibodies
- Patent Title (中): 抗GDF15抗体
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Application No.: US14137415Application Date: 2013-12-20
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Publication No.: US09175076B2Publication Date: 2015-11-03
- Inventor: Lorena Lerner , Sandra Abbott , Ailin Bai , Ting Chen , Maria Isabel Chiu , Qing Liu , Laura Poling , Nianjun Tao , Solly Weiler , Zhigang Weng , William M. Winston, Jr. , Jeno Gyuris
- Applicant: AVEO Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee: AVEO Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/18 ; C07K16/22 ; C12N1/21 ; C12N5/10 ; C12N5/12 ; C12N15/09 ; C12N15/13 ; C12N15/63 ; C12N15/64 ; A61K39/00
Abstract:
Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
Public/Granted literature
- US20140193427A1 ANTI-GDF15 ANTIBODIES Public/Granted day:2014-07-10
Information query
