Invention Grant
- Patent Title: Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation
- Patent Title (中): 人类脐带组织细胞用于在组织相容性错配移植中抑制不良免疫应答
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Application No.: US11611602Application Date: 2006-12-15
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Publication No.: US09175261B2Publication Date: 2015-11-03
- Inventor: Alexander M. Harmon , Janet E. Davis
- Applicant: Alexander M. Harmon , Janet E. Davis
- Applicant Address: US MA Raynham
- Assignee: DePuy Synthes Products, Inc.
- Current Assignee: DePuy Synthes Products, Inc.
- Current Assignee Address: US MA Raynham
- Agency: Johnson & Johnson
- Agent Bernard F. Plantz
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N5/073 ; A61K35/51 ; A61K35/12
Abstract:
Cell-based compositions and methods of their use to inhibit an adverse immune response such as graft versus host disease or rejection of transplanted tissue in a transplant recipient that is histocompatibility mismatched to the transplant donor are disclosed. The compositions and methods utilize postpartum-derived cells, such as cells derived from the placenta or umbilicus.
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