Invention Grant
- Patent Title: Process for the purification of tissue plasminogen activator
- Patent Title (中): 纯化组织纤溶酶原激活物的方法
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Application No.: US13885002Application Date: 2011-11-15
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Publication No.: US09175281B2Publication Date: 2015-11-03
- Inventor: Sanjay Bandyopadhyay , Sanjeev Kumar Mendiratta , Sushobhan Bandyopadhyay
- Applicant: Sanjay Bandyopadhyay , Sanjeev Kumar Mendiratta , Sushobhan Bandyopadhyay
- Applicant Address: IN Ahmedabad, Gujarat
- Assignee: Cadila Healthcare Limited
- Current Assignee: Cadila Healthcare Limited
- Current Assignee Address: IN Ahmedabad, Gujarat
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Priority: IN3127/MUM/2010 20101116
- International Application: PCT/IN2011/000790 WO 20111115
- International Announcement: WO2012/066569 WO 20120524
- Main IPC: C12N9/72
- IPC: C12N9/72
Abstract:
The present invention provides process of purification of tissue plasminogen activator (tPA) from a crude mixture or a partially purified mixture containing tPA protein and impurities by using hydrophobic interaction column chromatography, optionally in combination with ion exchange column chromatography.
Public/Granted literature
- US20130330808A1 NOVEL PROCESS FOR THE PURIFICATION OF TISSUE PLASMINOGEN ACTIVATOR Public/Granted day:2013-12-12
Information query
