An optical fiber having both low bend loss. The fiber has a central core region having refractive index Δ1, an inner cladding region having an outer radius r2>17 microns and refractive index Δ2 and a second cladding region surrounding the inner cladding region having refractive index Δ3. The fiber profile segments may be arranged so that Δ1>Δ3>Δ2. The fiber may exhibit a profile volume, V2 of the inner cladding region, calculated between r1 and r2, is at least 30% Δmicron2.