Invention Grant
US09198926B2 Methods and compositions comprising rifabutin, clarithromycin, and clofazimine 有权
包括利福布丁,克拉霉素和氯法齐明的方法和组合物

Methods and compositions comprising rifabutin, clarithromycin, and clofazimine
Abstract:
A composition of the present invention comprises an effective amount of rifabutin, an effective amount of clarithromycin, an effective amount of clofazimine, and an effective amount of an absorption enhancer, wherein the effective amount of the absorption enhancer is sufficient so that, when the composition is administered to a patient, an overall metabolism of clarithromycin as caused by rifabutin is reduced by shifting competing metabolism of rifabutin and clarithromycin so as to result in more active clarithromycin.
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