Invention Grant
- Patent Title: Stable pharmaceutical formulation of cabazitaxel
- Patent Title (中): 卡巴他赛的稳定药物制剂
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Application No.: US13967822Application Date: 2013-08-15
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Publication No.: US09198969B2Publication Date: 2015-12-01
- Inventor: Chiung Ju Tsai , Shin Hong Jang , Tsang-Miao Huang , Jhih Li He
- Applicant: Yung Shin Pharm. Ind. Co., Ltd.
- Applicant Address: TW Tachia Taichung
- Assignee: YUNG SHIN PHARM. IND. CO., LTD.
- Current Assignee: YUNG SHIN PHARM. IND. CO., LTD.
- Current Assignee Address: TW Tachia Taichung
- Agency: Perkins Coie LLP
- Agent Viola T. Kung
- Main IPC: A61K47/02
- IPC: A61K47/02 ; A61K31/337 ; A61K47/10 ; A61K9/00 ; A61K47/26
Abstract:
The present invention relates to a stable liquid cabazitaxel formulation in an enclosed container. The enclosed container comprises a liquid phase and an gaseous phase, wherein the liquid phase comprises cabazitaxel, polysorbate 80, ethanol, and one or more pH adjusters to maintain pH about 2.8-6.0, and the gaseous phase is saturated with CO2. The present invention is also directed to a process for preparing the enclosed liquid pharmaceutical composition container.
Public/Granted literature
- US20140171495A1 STABLE PHARMACEUTICAL FORMULATION OF CABAZITAXEL Public/Granted day:2014-06-19
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