Invention Grant
- Patent Title: TSH antibodies for point-of-care immunoassay formats
- Patent Title (中): 用于点护理免疫测定法的TSH抗体
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Application No.: US13306514Application Date: 2011-11-29
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Publication No.: US09199234B2Publication Date: 2015-12-01
- Inventor: Dan Wang , Gordon Bruce Collier , Joseph P. Skinner , Qiaoqiao Ruan , Sergey Y. Tetin
- Applicant: Dan Wang , Gordon Bruce Collier , Joseph P. Skinner , Qiaoqiao Ruan , Sergey Y. Tetin
- Applicant Address: US NJ Princeton
- Assignee: Abbott Point of Care Inc.
- Current Assignee: Abbott Point of Care Inc.
- Current Assignee Address: US NJ Princeton
- Main IPC: C12M3/00
- IPC: C12M3/00 ; C07K16/26 ; G01N33/543 ; G01N33/74 ; G01N33/76 ; B01L3/00 ; G01N33/53
Abstract:
The invention relates to antibody characteristics used to design a whole blood Point of Care Thyroid Stimulating Hormone (TSH) immunoassay using an ELISA sandwich assay lacking one or more wash steps between the antigen capture, detection antibody addition and substrate introduction steps. This invention exhibits low cross reactivity with biologically similar interfering cross reacting species, such as Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG).
Public/Granted literature
- US20120301896A1 TSH ANTIBODIES FOR POINT-OF-CARE IMMUNOASSAY FORMATS Public/Granted day:2012-11-29
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