Invention Grant
- Patent Title: Process for continous flow synthesis of beta-amino crotonate
- Patent Title (中): 巴豆酸β-氨基酸连续流动合成工艺
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Application No.: US14113804Application Date: 2012-04-25
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Publication No.: US09199913B2Publication Date: 2015-12-01
- Inventor: Arvind A. Kulkarni , Anna R. Joshi , Ramesh R. Joshi
- Applicant: Arvind A. Kulkarni , Anna R. Joshi , Ramesh R. Joshi
- Applicant Address: IN
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN
- Agency: Blank Rome LLP
- Priority: IN1205/DEL/2011 20110425; IN598/DEL/2012 20120302
- International Application: PCT/IN2012/000302 WO 20120425
- International Announcement: WO2012/147103 WO 20121101
- Main IPC: C07C229/00
- IPC: C07C229/00 ; C07C227/06
Abstract:
Beta aminocrotonates are important intermediates for the synthesis of Ca channel blockers. The processes available in the art are batch processes with yields about 85%. There are no continuous processes available for the synthesis of such compounds. This gap in the art is addressed by the invention by disclosing a continuous process resulting in high yields of beta amino crotonates.
Public/Granted literature
- US20140046090A1 PROCESS FOR CONTINOUS FLOW SYNTHESIS OF beta-AMINO CROTONATE Public/Granted day:2014-02-13
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