Invention Grant
US09199964B1 Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine
有权
3-（3-氯-1H-吡唑-1-基）吡啶的制备方法
- Patent Title: Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine
- Patent Title (中): 3-（3-氯-1H-吡唑-1-基）吡啶的制备方法
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Application No.: US14691714Application Date: 2015-04-21
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Publication No.: US09199964B1Publication Date: 2015-12-01
- Inventor: Qiang Yang , Beth Lorsbach , Xiaoyong Li , Gary Roth , David E. Podhorez
- Applicant: Dow AgroSciences LLC
- Applicant Address: US IN Indianapolis
- Assignee: Dow AgroSciences LLC
- Current Assignee: Dow AgroSciences LLC
- Current Assignee Address: US IN Indianapolis
- Agency: Barnes & Thornburg LLP
- Agent Carl D. Corvin
- Main IPC: C07D231/14
- IPC: C07D231/14 ; C07D403/04 ; A01N43/46 ; A61K31/415 ; C07D401/04
Abstract:
3-(3-Chloro-1H-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine.dihydrochloride with acrylonitrile to provide 1-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-3-amine, by oxidizing to provide 3-(3-amino-1H-pyrazol-1-yl)pyridine, and by converting the amino group to a chloro group by a Sandmeyer reaction.
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