Invention Grant
- Patent Title: Inhibitor compounds of phosphodiesterase type 10A
- Patent Title (中): 磷酸二酯酶10A型抑制剂化合物
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Application No.: US14189961Application Date: 2014-02-25
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Publication No.: US09200005B2Publication Date: 2015-12-01
- Inventor: Katja Jantos , Michael Ochse , Hervé Geneste , Jayne Froggett , Clarissa Jakob , Karla Drescher , Jürgen Dinges
- Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- Applicant Address: DE Wiesbaden US IL North Chicago
- Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee Address: DE Wiesbaden US IL North Chicago
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Main IPC: C07D495/04
- IPC: C07D495/04

Abstract:
The present invention relates to compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof: In formula I the variables X1 is CH or N, X2 is O or S and where R1, R2, R3, R4 and Q are as defined in the claims.The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A. Thus, the invention also relates to the use of the compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
Public/Granted literature
- US20140275069A1 Novel inhibitor compounds of phosphodiesterase type 10A Public/Granted day:2014-09-18
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