Invention Grant
US09200287B2 Phosphate-modified oligonucleotide analogs with enhanced immunostimulatory activity
有权
具有增强的免疫刺激活性的磷酸修饰的寡核苷酸类似物
- Patent Title: Phosphate-modified oligonucleotide analogs with enhanced immunostimulatory activity
- Patent Title (中): 具有增强的免疫刺激活性的磷酸修饰的寡核苷酸类似物
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Application No.: US12600368Application Date: 2008-05-15
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Publication No.: US09200287B2Publication Date: 2015-12-01
- Inventor: Eugen Uhlmann , Marion Jürk
- Applicant: Eugen Uhlmann , Marion Jürk
- Applicant Address: DE Frankfurt
- Assignee: AdiuTide Pharmaceuticals GmbH
- Current Assignee: AdiuTide Pharmaceuticals GmbH
- Current Assignee Address: DE Frankfurt
- Agency: Smith Patent
- Agent Chalin A. Smith
- International Application: PCT/IB2008/001206 WO 20080515
- International Announcement: WO2008/142513 WO 20081127
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C12N15/117 ; A61K31/7125 ; A61K45/06
Abstract:
The invention relates to oligonucleotides including at least one backbone modification and a pyrimidine-purine dinucleotide. The invention also relates to pharmaceutical compositions and methods of use thereof.
Public/Granted literature
- US20100261779A1 Phosphate-Modified Oligonucleotide Analogs with Enhanced Immunostimulatory Activity Public/Granted day:2010-10-14
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