There is provided an image pickup apparatus including: a control unit generating exposure time control data in which an exposure time of an image sensor is set in pixel region units; and an image sensor inputting the exposure time control data and carrying out image acquisition based on exposure time control in the pixel region units. The control unit successively and sequentially generates the exposure time control data in region units based on luminance information in the pixel region units that form part of a preceding picked-up image and outputs the exposure time control data to the image sensor. The image sensor inputs the exposure time control data in the region units from the control unit and successively and sequentially uses the inputted exposure time control data to carry out the image acquisition based on the exposure time control in the pixel region units.