Invention Grant
- Patent Title: Optimized in vivo delivery system with endosomolytic agents for nucleic acid conjugates
- Patent Title (中): 优化的体内递送系统与核酸缀合物的内分解酶
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Application No.: US13703965Application Date: 2011-06-21
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Publication No.: US09205099B2Publication Date: 2015-12-08
- Inventor: Jian-Sheng Sun , Marie Dutreix , Maria Quanz
- Applicant: Jian-Sheng Sun , Marie Dutreix , Maria Quanz
- Applicant Address: FR Evry FR Paris FR Paris
- Assignee: DNA THERAPEUTICS,INSTITUT CURIE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee: DNA THERAPEUTICS,INSTITUT CURIE,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
- Current Assignee Address: FR Evry FR Paris FR Paris
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Priority: EP10166936 20100622
- International Application: PCT/EP2011/060280 WO 20110621
- International Announcement: WO2011/161075 WO 20111229
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C07H21/02 ; A61K31/7088 ; A61K31/4706 ; A61K47/48
Abstract:
The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.
Public/Granted literature
- US20130131155A1 Optimized In Vivo Delivery System with Endosomolytic Agents for Nucleic Acid Conjugates Public/Granted day:2013-05-23
Information query
