Invention Grant
US09205140B2 MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer
有权
用于预防和治疗癌症的MSI特异性移码肽（FSP）
- Patent Title: MSI-specific frameshift peptides (FSP) for prevention and treatment of cancer
- Patent Title (中): 用于预防和治疗癌症的MSI特异性移码肽（FSP）
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Application No.: US13713753Application Date: 2012-12-13
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Publication No.: US09205140B2Publication Date: 2015-12-08
- Inventor: Matthias Kloor , Miriam Reuschenbach , Magnus von Knebel-Doeberitz
- Applicant: Ruprecht-Karls-Universitat Heidelberg
- Applicant Address: DE Heidelberg
- Assignee: Ruprecht-Karls-Universität
- Current Assignee: Ruprecht-Karls-Universität
- Current Assignee Address: DE Heidelberg
- Agency: Vedder Price P.C.
- Agent Thomas J. Kowalski; Deborah L. Lu
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K1/00 ; A61K39/00
Abstract:
Described is a vaccine for prevention and treatment of cancer characterized by microsatellite instability (MSI). The vaccine contains an MSI-specific frameshift peptide (FSP) generating humoral and cellular responses against tumor cells or a nucleic acid encoding said FSP. The vaccine of the present invention is particularly useful for the prevention/treatment of colorectal cancer, endometrial cancer, gastric cancer or small bowel cancer.
Public/Granted literature
- US20140170178A1 MSI-SPECIFIC FRAMESHIFT PEPTIDES (FSP) FOR PREVENTION AND TREATMENT OF CANCER Public/Granted day:2014-06-19
Information query
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